Startup Showcase: ATXA Therapeutics – Pioneering Breakthroughs in Pulmonary Arterial Hypertension Treatment

Advancing Hope and Transforming Lives through Innovative Drug Development

In this edition of, we are thrilled to showcase ATXA Therapeutics, an Irish-based biopharmaceutical company spearheading the late-stage preclinical and clinical development of groundbreaking small molecule drugs to treat Pulmonary Arterial Hypertension (PAH). Founded by Professor Therese Kinsella and fueled by over 20 years of cutting-edge research, ATXA Therapeutics is driven by a profound commitment to offer improved treatment options for PAH patients and new hope for those affected by this life-threatening condition.

The Vision and Mission

ATXA Therapeutics was established in May 2015 as a spin-out from University College Dublin, with a clear vision to transform the landscape of PAH treatment. Their primary mission is to advance clinical trials and obtain marketing authorization for novel therapies that can effectively address the unmet medical needs of PAH patients. By leveraging their extensive expertise in cardiovascular and cancer biology, ATXA is dedicated to developing small molecule drugs with the potential to revolutionize PAH treatment and beyond.

Pioneering Research and Development

At the heart of ATXA Therapeutics lies a deep commitment to research excellence and innovation. Backed by over €15 million in grant funding, the company has made significant strides in understanding the biology and signaling of human prostanoid receptors in both cardiovascular disease and oncology settings. Their groundbreaking discoveries have paved the way for the development of a series of novel, highly selective small molecule drugs with diverse applications in various target disease indications, including thrombosis/cardiovascular, oncology, and anti-inflammatory conditions.

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A Ray of Hope for PAH Patients

Pulmonary Arterial Hypertension is a severe and debilitating condition characterized by high blood pressure in the arteries of the lungs, leading to restricted blood flow and strain on the heart. Until now, treatment options for PAH have been limited, leaving many patients with a diminished quality of life and limited life expectancy. ATXA Therapeutics aims to change that. Their promising drug candidates represent a beacon of hope for PAH patients, offering potential breakthroughs that can significantly improve the standard of care and address the critical unmet medical needs of this vulnerable population.

Driving Late-Stage Development

Supported by funding from Enterprise Ireland and Science Foundation Ireland, ATXA Therapeutics is rapidly advancing the late-stage development of their novel therapies. The team boasts a wealth of expertise in drug discovery, early development, lead generation, lead optimization, candidate selection, medicinal chemistry, preclinical pharmacokinetics, intellectual property management, and commercialization. This collective knowledge enables ATXA to progress their drug candidates with efficiency and precision, ensuring that patients in need receive the best possible treatments as soon as possible.

Advancing Healthcare and Beyond

ATXA Therapeutics’ vision extends beyond the realm of PAH treatment. Their innovative small molecule drugs show potential in various therapeutic areas, promising to advance healthcare and transform the lives of patients worldwide. With a strong foundation of research and development expertise, ATXA is well-positioned to make significant contributions to the fields of cardiovascular medicine, oncology, anti-inflammatory therapies, and beyond.


ATXA Therapeutics Limited is a shining example of a groundbreaking startup dedicated to advancing medical science and transforming patient care. Their relentless pursuit of innovative solutions for Pulmonary Arterial Hypertension offers new hope to patients and medical professionals alike. We eagerly await the day when their novel therapies secure marketing authorization and become available to those in need, ushering in a new era of improved treatment options for PAH. Let us celebrate and support ATXA Therapeutics as they continue to push the boundaries of medical research and make a lasting impact on global healthcare.

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For more information about ATXA Therapeutics and their pioneering work, please visit their website and social media channels:

Website: ATXA Therapeutics

Twitter: ATXA Therapeutics on Twitter

Facebook: ATXA Therapeutics on Facebook

LinkedIn: ATXA Therapeutics on LinkedIn

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